BDBM50329817 (Z)-N-ethyl-N-methyl-3-((1-methylpiperidin-4-ylamino)(phenyl)methylene)-2-oxoindoline-6-carboxamide::CHEMBL1272077

SMILES CCN(C)C(=O)c1ccc2C(C(=NC3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=DUBRRYHAUGBPAB-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50329817   

TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329817((Z)-N-ethyl-N-methyl-3-((1-methylpiperidin-4-ylami...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329817((Z)-N-ethyl-N-methyl-3-((1-methylpiperidin-4-ylami...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329817((Z)-N-ethyl-N-methyl-3-((1-methylpiperidin-4-ylami...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed