BDBM50329652 (R)-1,1,1-trifluoropropan-2-yl 9H-pyrido[3,4-b]indole-3-carboxylate::CHEMBL1270943

SMILES C[C@@H](OC(=O)c1cc2c(cn1)[nH]c1ccccc21)C(F)(F)F

InChI Key InChIKey=ISJKPUWGGXLQCI-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50329652   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50329652((R)-1,1,1-trifluoropropan-2-yl 9H-pyrido[3,4-b]ind...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha-1-beta-3-gamma-2 receptor expressed in HEK cells by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50329652((R)-1,1,1-trifluoropropan-2-yl 9H-pyrido[3,4-b]ind...)
Affinity DataKi:  343nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha-2-beta-3-gamma-2 receptor expressed in HEK cells by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50329652((R)-1,1,1-trifluoropropan-2-yl 9H-pyrido[3,4-b]ind...)
Affinity DataKi:  453nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha-3-beta-3-gamma-2 receptor expressed in HEK cells by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50329652((R)-1,1,1-trifluoropropan-2-yl 9H-pyrido[3,4-b]ind...)
Affinity DataKi:  1.85E+3nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha-5-beta-3-gamma-2 receptor expressed in HEK cells by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50329652((R)-1,1,1-trifluoropropan-2-yl 9H-pyrido[3,4-b]ind...)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha-6-beta-3-gamma-2 receptor expressed in HEK cells by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetGABA A receptor alpha-4/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50329652((R)-1,1,1-trifluoropropan-2-yl 9H-pyrido[3,4-b]ind...)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha-4-beta-3-gamma-2 receptor expressed in HEK cells by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed