BDBM50329211 5-(4-chlorophenyl)-N-(2-methylbenzyl)nicotinamide::CHEMBL1269882

SMILES Cc1ccccc1CNC(=O)c1cncc(c1)-c1ccc(Cl)cc1

InChI Key InChIKey=MLDMXXWILKZITA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50329211   

TargetSodium channel protein type 10 subunit alpha(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329211(5-(4-chlorophenyl)-N-(2-methylbenzyl)nicotinamide ...)
Affinity DataIC50: 30nMAssay Description:Inhibition of mouse NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329211(5-(4-chlorophenyl)-N-(2-methylbenzyl)nicotinamide ...)
Affinity DataIC50: 9nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329211(5-(4-chlorophenyl)-N-(2-methylbenzyl)nicotinamide ...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human NaV1.2 by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329211(5-(4-chlorophenyl)-N-(2-methylbenzyl)nicotinamide ...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed