BDBM50329202 5-(4-cyanophenyl)-N-(3,5-dimethylphenyl)nicotinamide::CHEMBL1271309

SMILES Cc1cc(C)cc(NC(=O)c2cncc(c2)-c2ccc(cc2)C#N)c1

InChI Key InChIKey=VAOBPPDVUDDCKB-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50329202   

LigandPNGBDBM50329202(5-(4-cyanophenyl)-N-(3,5-dimethylphenyl)nicotinami...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329202(5-(4-cyanophenyl)-N-(3,5-dimethylphenyl)nicotinami...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KCNQ2/Q3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329202(5-(4-cyanophenyl)-N-(3,5-dimethylphenyl)nicotinami...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human ERG by Isotopic flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329202(5-(4-cyanophenyl)-N-(3,5-dimethylphenyl)nicotinami...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NaV1.5 by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329202(5-(4-cyanophenyl)-N-(3,5-dimethylphenyl)nicotinami...)
Affinity DataIC50: 91nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329202(5-(4-cyanophenyl)-N-(3,5-dimethylphenyl)nicotinami...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CaV2.2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329202(5-(4-cyanophenyl)-N-(3,5-dimethylphenyl)nicotinami...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329202(5-(4-cyanophenyl)-N-(3,5-dimethylphenyl)nicotinami...)
Affinity DataIC50: 190nMAssay Description:Inhibition of mouse NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed