BDBM50328804 CHEMBL1269951::rac-1,2,5-trimethyl-4-(naphthalen-1-ylethynyl)piperidin-4-yl acetate

SMILES CC1CC(OC(C)=O)(C#Cc2cccc3ccccc23)C(C)CN1C

InChI Key InChIKey=RENBHJFCFJUFID-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328804   

TargetHistamine H3 receptor(Mouse)
Athersys

Curated by ChEMBL
LigandPNGBDBM50328804(rac-1,2,5-trimethyl-4-(naphthalen-1-ylethynyl)pipe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against mouse histamine H3 receptor expressed in human HT1080 cells assessed as inhibition of (R)-alpha-methylhistamine-induced i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50328804(rac-1,2,5-trimethyl-4-(naphthalen-1-ylethynyl)pipe...)
Affinity DataIC50: 5.51E+3nMAssay Description:Antagonist activity against human histamine H3 receptor expressed in human HT1080 cells assessed as inhibition of (R)-alpha-methylhistamine-induced i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed