BDBM50328803 (2S,4R,5R)-1,2,5-trimethyl-4-(naphthalen-1-ylethynyl)piperidin-4-ol::CHEMBL1269950

SMILES C[C@H]1C[C@](O)(C#Cc2cccc3ccccc23)[C@H](C)CN1C

InChI Key InChIKey=UATGXLFLKRXZBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328803   

TargetHistamine H3 receptor(Mouse)
Athersys

Curated by ChEMBL
LigandPNGBDBM50328803((2S,4R,5R)-1,2,5-trimethyl-4-(naphthalen-1-ylethyn...)
Affinity DataIC50: 1.32E+3nMAssay Description:Antagonist activity against mouse histamine H3 receptor expressed in human HT1080 cells assessed as inhibition of (R)-alpha-methylhistamine-induced i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50328803((2S,4R,5R)-1,2,5-trimethyl-4-(naphthalen-1-ylethyn...)
Affinity DataIC50: 41nMAssay Description:Antagonist activity against human histamine H3 receptor expressed in human HT1080 cells assessed as inhibition of (R)-alpha-methylhistamine-induced i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed