BDBM50328484 1-Methyl-4-(8-(5-methylthiophen-2-yl)-10,11-dihydrodibenzo-[b,f]thiepin-10-yl)piperazine::CHEMBL1259005

SMILES CN1CCN(CC1)C1Cc2ccccc2Sc2ccc(cc12)-c1ccc(C)s1

InChI Key InChIKey=JLCDZKSQUUANJO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50328484   

TargetAlpha-1A adrenergic receptor(Bovine)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328484(1-Methyl-4-(8-(5-methylthiophen-2-yl)-10,11-dihydr...)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]prozosin from bovine cloned Alpha-1A receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Golden hamster)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328484(1-Methyl-4-(8-(5-methylthiophen-2-yl)-10,11-dihydr...)
Affinity DataKi:  0.720nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha-1b receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328484(1-Methyl-4-(8-(5-methylthiophen-2-yl)-10,11-dihydr...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]prozosin from human cloned dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328484(1-Methyl-4-(8-(5-methylthiophen-2-yl)-10,11-dihydr...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]prozosin from rat cloned alpha1d receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed