BDBM50328476 1-(2-(4-(1-(4-fluorophenyl)-5-((2-methyl-2H-tetrazol-5-yl)methyl)-1H-indol-3-yl)piperidin-1-yl)ethyl)imidazolidin-2-one::CHEMBL1259188

SMILES Cn1nnc(Cc2ccc3n(cc(C4CCN(CCN5CCNC5=O)CC4)c3c2)-c2ccc(F)cc2)n1

InChI Key InChIKey=FGHKCRNDQSRICR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50328476   

TargetAlpha-1B adrenergic receptor(Golden hamster)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328476(1-(2-(4-(1-(4-fluorophenyl)-5-((2-methyl-2H-tetraz...)
Affinity DataKi:  0.560nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha-1b receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Bovine)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328476(1-(2-(4-(1-(4-fluorophenyl)-5-((2-methyl-2H-tetraz...)
Affinity DataKi:  0.660nMAssay Description:Displacement of [3H]prozosin from bovine cloned Alpha-1A receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328476(1-(2-(4-(1-(4-fluorophenyl)-5-((2-methyl-2H-tetraz...)
Affinity DataKi:  0.770nMAssay Description:Displacement of [3H]prozosin from rat cloned alpha1d receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328476(1-(2-(4-(1-(4-fluorophenyl)-5-((2-methyl-2H-tetraz...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]prozosin from human cloned dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed