BDBM50328329 1-(4-fluorophenoxy)-3-(1-(5-phenylthieno[2,3-d]pyrimidin-4-yl)piperidin-4-ylamino)propan-2-ol::CHEMBL1258370

SMILES OC(CNC1CCN(CC1)c1ncnc2scc(-c3ccccc3)c12)COc1ccc(F)cc1

InChI Key InChIKey=IRRIBWMUPMJWTM-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50328329   

TargetBeta-3 adrenergic receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50328329(1-(4-fluorophenoxy)-3-(1-(5-phenylthieno[2,3-d]pyr...)
Affinity DataEC50:  92nMAssay Description:Agonist activity at human recombinant adrenergic beta3 receptor expressed in CHO cells assessed as cyclic AMP formation by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50328329(1-(4-fluorophenoxy)-3-(1-(5-phenylthieno[2,3-d]pyr...)
Affinity DataKi:  55nMAssay Description:Displacement of [125I]-cyanopindolol from human adrenergic beta2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50328329(1-(4-fluorophenoxy)-3-(1-(5-phenylthieno[2,3-d]pyr...)
Affinity DataKi:  88nMAssay Description:Displacement of [125I]-cyanopindolol from human adrenergic beta3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50328329(1-(4-fluorophenoxy)-3-(1-(5-phenylthieno[2,3-d]pyr...)
Affinity DataKi:  268nMAssay Description:Agonist activity at human recombinant adrenergic beta-1 receptor expressed in CHO cells assessed as cyclic AMP formation by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed