BDBM50328323 5-(2-hydroxy-3-(1-(5-phenylthieno[2,3-d]pyrimidin-4-yl)piperidin-4-ylamino)propoxy)-2-(hydroxymethyl)phenol::CHEMBL1257324

SMILES OCc1ccc(OCC(O)CNC2CCN(CC2)c2ncnc3scc(-c4ccccc4)c23)cc1O

InChI Key InChIKey=WBFTUDPFMMKOMZ-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328323   

TargetBeta-3 adrenergic receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50328323(5-(2-hydroxy-3-(1-(5-phenylthieno[2,3-d]pyrimidin-...)
Affinity DataEC50:  97nMAssay Description:Displacement of [125I]-cyanopindolol from human adrenergic beta3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50328323(5-(2-hydroxy-3-(1-(5-phenylthieno[2,3-d]pyrimidin-...)
Affinity DataKi:  259nMAssay Description:Displacement of [125I]-cyanopindolol from human adrenergic beta2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50328323(5-(2-hydroxy-3-(1-(5-phenylthieno[2,3-d]pyrimidin-...)
Affinity DataKi:  620nMAssay Description:Displacement of [125I]-cyanopindolol from human adrenergic beta3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed