BDBM50328102 1-(3-{[5-Morpholin-4-yl)-2,2-dimethyl-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-yl]amino}propyl)pyrrolilydin-2-one::CHEMBL1257421

SMILES CC1(C)CCc2c(C1)c1c(nc2N2CCOCC2)sc2c(NCCCN3CCCC3=O)ncnc12

InChI Key InChIKey=YFBAOXITVIDIPH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328102   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328102(1-(3-{[5-Morpholin-4-yl)-2,2-dimethyl-1,2,3,4-tetr...)
Affinity DataIC50: 18nMAssay Description:Inhibition of PDE4A4 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328102(1-(3-{[5-Morpholin-4-yl)-2,2-dimethyl-1,2,3,4-tetr...)
Affinity DataIC50: 21nMAssay Description:Inhibition of PDE4B1 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328102(1-(3-{[5-Morpholin-4-yl)-2,2-dimethyl-1,2,3,4-tetr...)
Affinity DataIC50: 61nMAssay Description:Inhibition of PDE4D3 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed