BDBM50328095 CHEMBL1258806::N5,2,2-Trimethyl-N8-(2-morpholin-4-ylethyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-5,8-diamine

SMILES CNc1nc2sc3c(NCCN4CCOCC4)ncnc3c2c2CC(C)(C)CCc12

InChI Key InChIKey=CKDYACSCRUTGHR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328095   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328095(N5,2,2-Trimethyl-N8-(2-morpholin-4-ylethyl)-1,2,3,...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of PDE4D3 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328095(N5,2,2-Trimethyl-N8-(2-morpholin-4-ylethyl)-1,2,3,...)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of PDE4B1 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328095(N5,2,2-Trimethyl-N8-(2-morpholin-4-ylethyl)-1,2,3,...)
Affinity DataIC50: 18nMAssay Description:Inhibition of PDE4A4 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed