BDBM50328047 CHEMBL1257184::N-((2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-(1-(1-((trimethylsilyl)methyl)-1H-1,2,3-triazol-4-yl)cyclohexylamino)butan-2-yl)acetamide

SMILES CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CNC1(CCCCC1)c1cn(C[Si](C)(C)C)nn1

InChI Key InChIKey=ZMXVFQQEYSIUTL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328047   

TargetCathepsin D(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328047(N-((2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-(1-(...)
Affinity DataIC50: 12nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328047(N-((2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-(1-(...)
Affinity DataIC50: 154nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed