BDBM50327857 1-(4-Isopropylphenyl)-3-(1-propionylpiperidin-4-yl)urea::CHEMBL1257877::US9296693, 14

SMILES CCC(=O)N1CCC(CC1)NC(=O)Nc1ccc(cc1)C(C)C

InChI Key InChIKey=RJETXSSAWCBJKU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327857   

TargetBifunctional epoxide hydrolase 2(Human)
University of California

US Patent
LigandPNGBDBM50327857(1-(4-Isopropylphenyl)-3-(1-propionylpiperidin-4-yl...)
Affinity DataIC50: 2.80nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2017
Entry Details
Go to US Patent

TargetBifunctional epoxide hydrolase 2(Mouse)
University of California

US Patent
LigandPNGBDBM50327857(1-(4-Isopropylphenyl)-3-(1-propionylpiperidin-4-yl...)
Affinity DataIC50: 3.30nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2017
Entry Details
Go to US Patent

TargetBifunctional epoxide hydrolase 2(Human)
University of California

US Patent
LigandPNGBDBM50327857(1-(4-Isopropylphenyl)-3-(1-propionylpiperidin-4-yl...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
University of California

US Patent
LigandPNGBDBM50327857(1-(4-Isopropylphenyl)-3-(1-propionylpiperidin-4-yl...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed