BDBM50327856 1-(1-(5-(Dimethylamino)naphthalen-1-ylsulfonyl)piperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea::CHEMBL1257880::US8501783, 1710::US9296693, 59

SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=SDLXTGGQDFKXAN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50327856   

TargetEpoxide hydrolase 1(Human)
University of California

US Patent
LigandPNGBDBM50327856(CHEMBL1257880 | US8501783, 1710 | 1-(1-(5-(Dimethy...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2013
Entry Details
Go to US Patent

TargetBifunctional epoxide hydrolase 2(Human)
University of California

US Patent
LigandPNGBDBM50327856(CHEMBL1257880 | US8501783, 1710 | 1-(1-(5-(Dimethy...)
Affinity DataIC50: 0.800nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2017
Entry Details
Go to US Patent

TargetBifunctional epoxide hydrolase 2(Human)
University of California

US Patent
LigandPNGBDBM50327856(CHEMBL1257880 | US8501783, 1710 | 1-(1-(5-(Dimethy...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed