BDBM50327852 1-(4-(Trifluoromethoxy)phenyl)-3-(1-(3,4,5-trihydroxybenzoyl)piperidin-4-yl)urea::CHEMBL1257518::US9296693, 54

SMILES Oc1cc(cc(O)c1O)C(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=IZEJBCBZKQOXMT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327852   

TargetBifunctional epoxide hydrolase 2(Human)
University of California

US Patent
LigandPNGBDBM50327852(1-(4-(Trifluoromethoxy)phenyl)-3-(1-(3,4,5-trihydr...)
Affinity DataIC50: 0.5nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2017
Entry Details
Go to US Patent

TargetBifunctional epoxide hydrolase 2(Mouse)
University of California

US Patent
LigandPNGBDBM50327852(1-(4-(Trifluoromethoxy)phenyl)-3-(1-(3,4,5-trihydr...)
Affinity DataIC50: 2.70nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2017
Entry Details
Go to US Patent

TargetBifunctional epoxide hydrolase 2(Human)
University of California

US Patent
LigandPNGBDBM50327852(1-(4-(Trifluoromethoxy)phenyl)-3-(1-(3,4,5-trihydr...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
University of California

US Patent
LigandPNGBDBM50327852(1-(4-(Trifluoromethoxy)phenyl)-3-(1-(3,4,5-trihydr...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed