BDBM50327738 CHEMBL1257981::N-ethyl-N-((5-fluoro-1-octyl-1H-indol-3-yl)methyl)ethanamine

SMILES CCCCCCCCn1cc(CN(CC)CC)c2cc(F)ccc12

InChI Key InChIKey=SSNMQSSXTMNMQL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327738   

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50327738(N-ethyl-N-((5-fluoro-1-octyl-1H-indol-3-yl)methyl)...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of recombinant ICMT expressed in Sf9 cells using [3H] AdoMet after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50327738(N-ethyl-N-((5-fluoro-1-octyl-1H-indol-3-yl)methyl)...)
Affinity DataIC50: 4.42E+3nMAssay Description:Inhibition of recombinant Icmt (unknown origin) expressed in Sf9 cells assessed as transfer of methyl group from [3H]-S-adenosylmethionine to [3H]-bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed