BDBM50327676 CHEMBL1084097::Dibenzo[b,f][1,4]oxazepine-6-carboxylic acid amide::dibenzo[b,f][1,4]oxazepine-6-carboxamide

SMILES NC(=O)c1cccc2N=Cc3ccccc3Oc12

InChI Key InChIKey=PTHBOTMILXORGK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327676   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50327676(Dibenzo[b,f][1,4]oxazepine-6-carboxylic acid amide...)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50327676(Dibenzo[b,f][1,4]oxazepine-6-carboxylic acid amide...)
Affinity DataEC50:  0.115nMAssay Description:Activation of human TRPA1 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed