BDBM50327652 6,7-Dihydroxycoumarinyl-4-acetic::CHEMBL1255817

SMILES OC(=O)Cc1cc(=O)oc2cc(O)c(O)cc12

InChI Key InChIKey=VZBNZFYHLQRFPS-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327652   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50327652(6,7-Dihydroxycoumarinyl-4-acetic | CHEMBL1255817)
Affinity DataKi:  9.36E+3nMAssay Description:Displacement of FAM-Bid peptide from recombinant N-terminal His6x-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) incubated for 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50327652(6,7-Dihydroxycoumarinyl-4-acetic | CHEMBL1255817)
Affinity DataIC50: 3.37E+4nMAssay Description:Displacement of FAM-Bid peptide from recombinant N-terminal His6x-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) incubated for 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50327652(6,7-Dihydroxycoumarinyl-4-acetic | CHEMBL1255817)
Affinity DataIC50: 6.33E+4nMAssay Description:Inhibition human recombinant aldose reductase 1 by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSorbitol dehydrogenase(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50327652(6,7-Dihydroxycoumarinyl-4-acetic | CHEMBL1255817)
Affinity DataIC50: 3.35E+5nMAssay Description:Inhibition sorbitol dehydrogenase by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed