BDBM50327294 CHEMBL1258168::N-((4'-(1-amino-3-(4-(2-(2,6-dichloro-4-methylphenoxy)ethoxy)phenyl)propan-2-yl)-3'-methylbiphenyl-2-yl)methyl)acetamide

SMILES CC(=O)NCc1ccccc1-c1ccc(C(CN)Cc2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)c(C)c1

InChI Key InChIKey=XMURKBGOEUGSJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327294   

TargetRenin(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50327294(N-((4'-(1-amino-3-(4-(2-(2,6-dichloro-4-methylphen...)
Affinity DataIC50: 138nMAssay Description:Inhibition of human recombinant renin in plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetRenin(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50327294(N-((4'-(1-amino-3-(4-(2-(2,6-dichloro-4-methylphen...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human recombinant renin in phosphate bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed