BDBM50327282 2-(2'-chloro-3-fluorobiphenyl-4-yl)-3-(4-(2-(2,6-dichloro-4-methylphenoxy)ethoxy)phenyl)propan-1-amine::CHEMBL1257349

SMILES Cc1cc(Cl)c(OCCOc2ccc(CC(CN)c3ccc(cc3F)-c3ccccc3Cl)cc2)c(Cl)c1

InChI Key InChIKey=ZUNPKGJBZFDEPB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327282   

TargetRenin(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50327282(2-(2'-chloro-3-fluorobiphenyl-4-yl)-3-(4-(2-(2,6-d...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant renin in phosphate bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetRenin(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50327282(2-(2'-chloro-3-fluorobiphenyl-4-yl)-3-(4-(2-(2,6-d...)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human recombinant renin in plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed