BDBM50327281 2-(2'-chloro-3-methoxybiphenyl-4-yl)-3-(4-(2-(2,6-dichloro-4-methylphenoxy)ethoxy)phenyl)propan-1-amine::CHEMBL1257229

SMILES COc1cc(ccc1C(CN)Cc1ccc(OCCOc2c(Cl)cc(C)cc2Cl)cc1)-c1ccccc1Cl

InChI Key InChIKey=RIINYUGVNAMTRL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327281   

TargetRenin(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50327281(2-(2'-chloro-3-methoxybiphenyl-4-yl)-3-(4-(2-(2,6-...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant renin in phosphate bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetRenin(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50327281(2-(2'-chloro-3-methoxybiphenyl-4-yl)-3-(4-(2-(2,6-...)
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of human recombinant renin in plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed