BDBM50327180 5-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-pyrazol-1-yl)-N-(cyanomethyl)-2-methylbenzamide::CHEMBL1257930

SMILES Cc1ccc(cc1C(=O)NCC#N)-n1nc(cc1NC(=O)Nc1cccc2ccccc12)C(C)(C)C

InChI Key InChIKey=AUISCILDAZIGDV-UHFFFAOYSA-N

Data  1 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327180   

TargetMitogen-activated protein kinase 14(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327180(5-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-pyr...)
Affinity DataKd:  55nMAssay Description:Binding affinity to full-length GST-tagged p38alpha by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327180(5-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-pyr...)
Affinity DataKi:  252nMAssay Description:Binding affinity to full-length GST-tagged p38alpha after 2.5 hrs by TR-FRET competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed