BDBM50327148 (R)-methyl 2-(4-iodophenyl)-2-((R)-piperidin-2-yl)acetate::CHEMBL1253735

SMILES COC(=O)[C@@H]([C@H]1CCCCN1)c1ccc(I)cc1

InChI Key InChIKey=KYFGACYORZGXNM-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50327148   

TargetSodium-dependent dopamine transporter(Rat)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50327148((R)-methyl 2-(4-iodophenyl)-2-((R)-piperidin-2-yl)...)
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]WIN 35428 from Sprague-Dawley rat striatal tissue after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50327148((R)-methyl 2-(4-iodophenyl)-2-((R)-piperidin-2-yl)...)
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Duquesne University Mylan School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50327148((R)-methyl 2-(4-iodophenyl)-2-((R)-piperidin-2-yl)...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed