BDBM50327101 5-(4-Butoxy-3-{[2-fluoro-4-(trifluoromethyl)phenylamido]methyl}phenyl)pyridine-3-carboxylic acid::CHEMBL1254673

SMILES CCCCOc1ccc(cc1CNC(=O)c1ccc(cc1F)C(F)(F)F)-c1cncc(c1)C(O)=O

InChI Key InChIKey=QWBFMZFPZCWMRU-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50327101   

TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50327101(5-(4-Butoxy-3-{[2-fluoro-4-(trifluoromethyl)phenyl...)
Affinity DataEC50:  220nMAssay Description:Partial agonist activity at human recombinant PPARdelta LBD expressed in HEK293 cells co-transfected with Gal4 assessed as beta-galactosidase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50327101(5-(4-Butoxy-3-{[2-fluoro-4-(trifluoromethyl)phenyl...)
Affinity DataEC50:  4.00E+3nMAssay Description:Partial agonist activity at human recombinant PPARalpha LBD expressed in HEK293 cells co-transfected with Gal4 assessed as beta-galactosidase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50327101(5-(4-Butoxy-3-{[2-fluoro-4-(trifluoromethyl)phenyl...)
Affinity DataEC50:  220nMAssay Description:Partial agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50327101(5-(4-Butoxy-3-{[2-fluoro-4-(trifluoromethyl)phenyl...)
Affinity DataEC50:  4.00E+3nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50327101(5-(4-Butoxy-3-{[2-fluoro-4-(trifluoromethyl)phenyl...)
Affinity DataEC50:  2.20E+5nMAssay Description:Partial agonist activity at PPARdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed