BDBM50326715 CHEMBL456263::N-(6-methoxypyridin-3-yl)-1,2-dimethyl-N-((5-o-tolylpyridin-2-yl)methyl)-1H-imidazole-4-sulfonamide

SMILES COc1ccc(cn1)N(Cc1ccc(cn1)-c1ccccc1C)S(=O)(=O)c1cn(C)c(C)n1

InChI Key InChIKey=GNURBBYUBWBREM-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50326715   

TargetOxytocin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50326715(N-(6-methoxypyridin-3-yl)-1,2-dimethyl-N-((5-o-tol...)
Affinity DataKi:  0.794nMAssay Description:Displacement of 3H-oxytocin from human recombinant oxytocin receptor expressed in CHO cells by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOxytocin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50326715(N-(6-methoxypyridin-3-yl)-1,2-dimethyl-N-((5-o-tol...)
Affinity DataKi:  9.10nMAssay Description:Displacement of [3H]-oxytocin from oxytocin receptor in human uterus tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetOxytocin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50326715(N-(6-methoxypyridin-3-yl)-1,2-dimethyl-N-((5-o-tol...)
Affinity DataKi:  12.6nMAssay Description:Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetVasopressin V1b receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50326715(N-(6-methoxypyridin-3-yl)-1,2-dimethyl-N-((5-o-tol...)
Affinity DataKi:  31.6nMAssay Description:Binding affinity to vasopressin V1b receptor by filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50326715(N-(6-methoxypyridin-3-yl)-1,2-dimethyl-N-((5-o-tol...)
Affinity DataKi:  63.1nMAssay Description:Binding affinity to vasopressin V1a receptor by filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50326715(N-(6-methoxypyridin-3-yl)-1,2-dimethyl-N-((5-o-tol...)
Affinity DataKi:  1.26E+4nMAssay Description:Binding affinity to vasopressin V2 receptor by filtration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed