BDBM50326610 2-Amino-4-(m-bromoanilino)-6-benzyl-7-methyl-pyrrolo-[2,3-d]pyrimidine::CHEMBL1254285

SMILES Cn1c(Cc2ccccc2)cc2c(Nc3cccc(Br)c3)nc(N)nc12

InChI Key InChIKey=KCVASMRHHADGSC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326610   

TargetEpidermal growth factor receptor(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50326610(2-Amino-4-(m-bromoanilino)-6-benzyl-7-methyl-pyrro...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of EGFR expressed in human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50326610(2-Amino-4-(m-bromoanilino)-6-benzyl-7-methyl-pyrro...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of VEGFR2 expressed in human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50326610(2-Amino-4-(m-bromoanilino)-6-benzyl-7-methyl-pyrro...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of PDGFRbeta expressed in human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed