BDBM50326517 (E)-4-[(4-Fluorobenzyl)methylamino]-but-2-enoic acid[4-(3-chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinoline-6-yl]amide::CHEMBL1243254

SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)Cc1ccc(F)cc1

InChI Key InChIKey=KEPKJFBNFMUYMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326517   

TargetEpidermal growth factor receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326517((E)-4-[(4-Fluorobenzyl)methylamino]-but-2-enoic ac...)
Affinity DataIC50: 0.570nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326517((E)-4-[(4-Fluorobenzyl)methylamino]-but-2-enoic ac...)
Affinity DataIC50: 16.5nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed