BDBM50326515 (E)-N-[4-(3-Chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl]-3-[1-(2-fluoroethyl)-1H-[1,2,3]triazol-4-yl]-acrylamide::CHEMBL1243346

SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\c1cn(CCF)nn1

InChI Key InChIKey=ZSMLGVFRQDVJPG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326515   

TargetEpidermal growth factor receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326515((E)-N-[4-(3-Chloro-4-fluorophenylamino)-3-cyano-7-...)
Affinity DataIC50: 4.05nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326515((E)-N-[4-(3-Chloro-4-fluorophenylamino)-3-cyano-7-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed