BDBM50326490 1,1-diallyl-3-(5-hydroxy-4,6-dimethyl-2-oxoindolin-3-ylidene)thiourea::CHEMBL1243064

SMILES Cc1cc2NC(=O)C(=NC(=S)N(CC=C)CC=C)c2c(C)c1O

InChI Key InChIKey=MTDYVCJCWISUMJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326490   

TargetNADPH oxidase 4(Human)
Vichem Chemie Research

Curated by ChEMBL
LigandPNGBDBM50326490(1,1-diallyl-3-(5-hydroxy-4,6-dimethyl-2-oxoindolin...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed