BDBM50326413 4-(9H-purin-6-ylamino)benzamide::CHEMBL1241463

SMILES NC(=O)c1ccc(Nc2ncnc3nc[nH]c23)cc1

InChI Key InChIKey=HNZGNBCVBQTPNR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326413   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50326413(4-(9H-purin-6-ylamino)benzamide | CHEMBL1241463)
Affinity DataIC50: 160nMAssay Description:Inhibition of MNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50326413(4-(9H-purin-6-ylamino)benzamide | CHEMBL1241463)
Affinity DataIC50: 60nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2020
Entry Details Article
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50326413(4-(9H-purin-6-ylamino)benzamide | CHEMBL1241463)
Affinity DataIC50: 60nMAssay Description:Inhibition of Mnk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed