BDBM50326265 CHEMBL1243298::quilostigmine

SMILES CN1CC[C@]2(C)[C@H]1N(C)c1ccc(OC(=O)N3CCc4ccccc4C3)cc21

InChI Key InChIKey=IIFRKALDATVOJE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326265   

TargetAcetylcholinesterase(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50326265(quilostigmine | CHEMBL1243298)
Affinity DataIC50: 148nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50326265(quilostigmine | CHEMBL1243298)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed