BDBM50326117 1-Benzyl-1,4-dihydro-4-oxo-3-pyridinesulfonamide::CHEMBL1240573

SMILES NS(=O)(=O)c1cn(Cc2ccccc2)ccc1=O

InChI Key InChIKey=WIIFYOJVUKTZDG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50326117   

TargetCarbonic anhydrase 9(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326117(1-Benzyl-1,4-dihydro-4-oxo-3-pyridinesulfonamide |...)
Affinity DataKi:  7.80nMAssay Description:Inhibition of human cloned catalytic domain of CA9 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326117(1-Benzyl-1,4-dihydro-4-oxo-3-pyridinesulfonamide |...)
Affinity DataKi:  45.2nMAssay Description:Inhibition of human cloned catalytic domain of CA12 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326117(1-Benzyl-1,4-dihydro-4-oxo-3-pyridinesulfonamide |...)
Affinity DataKi:  80nMAssay Description:Inhibition of human cloned CA2 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326117(1-Benzyl-1,4-dihydro-4-oxo-3-pyridinesulfonamide |...)
Affinity DataKi:  4.12E+3nMAssay Description:Inhibition of human cloned CA1 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed