BDBM50326113 1-(3,4-Dichlorophenacyl)-1,4-dihydro-4-oxo-3-pyridinesulfonamide::CHEMBL1242706

SMILES NS(=O)(=O)c1cn(CC(=O)c2ccc(Cl)c(Cl)c2)ccc1=O

InChI Key InChIKey=MDABKLUMWAFTGF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50326113   

TargetCarbonic anhydrase 9(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326113(1-(3,4-Dichlorophenacyl)-1,4-dihydro-4-oxo-3-pyrid...)
Affinity DataKi:  8.60nMAssay Description:Inhibition of human cloned catalytic domain of CA9 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326113(1-(3,4-Dichlorophenacyl)-1,4-dihydro-4-oxo-3-pyrid...)
Affinity DataKi:  25.4nMAssay Description:Inhibition of human cloned catalytic domain of CA12 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326113(1-(3,4-Dichlorophenacyl)-1,4-dihydro-4-oxo-3-pyrid...)
Affinity DataKi:  114nMAssay Description:Inhibition of human cloned CA2 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326113(1-(3,4-Dichlorophenacyl)-1,4-dihydro-4-oxo-3-pyrid...)
Affinity DataKi:  1.18E+3nMAssay Description:Inhibition of human cloned CA1 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed