BDBM50326109 1,4-Dihydro-4-oxo-1-(3-sulfamoylpyrid-4-yl)-3-pyridiensulfonamide::CHEMBL1242890

SMILES NS(=O)(=O)c1cnccc1-n1ccc(=O)c(c1)S(N)(=O)=O

InChI Key InChIKey=MYLWHPNSZBTYBL-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50326109   

TargetCarbonic anhydrase 9(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326109(1,4-Dihydro-4-oxo-1-(3-sulfamoylpyrid-4-yl)-3-pyri...)
Affinity DataKi:  5.20nMAssay Description:Inhibition of human cloned catalytic domain of CA9 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326109(1,4-Dihydro-4-oxo-1-(3-sulfamoylpyrid-4-yl)-3-pyri...)
Affinity DataKi:  5.20nMAssay Description:Inhibition of human cloned carbonic anhydrase 9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326109(1,4-Dihydro-4-oxo-1-(3-sulfamoylpyrid-4-yl)-3-pyri...)
Affinity DataKi:  8.70nMAssay Description:Inhibition of human cloned catalytic domain of CA12 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326109(1,4-Dihydro-4-oxo-1-(3-sulfamoylpyrid-4-yl)-3-pyri...)
Affinity DataKi:  8.70nMAssay Description:Inhibition of human cloned carbonic anhydrase 12 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326109(1,4-Dihydro-4-oxo-1-(3-sulfamoylpyrid-4-yl)-3-pyri...)
Affinity DataKi:  50.5nMAssay Description:Inhibition of human cloned CA2 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326109(1,4-Dihydro-4-oxo-1-(3-sulfamoylpyrid-4-yl)-3-pyri...)
Affinity DataKi:  50.5nMAssay Description:Inhibition of human cloned carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326109(1,4-Dihydro-4-oxo-1-(3-sulfamoylpyrid-4-yl)-3-pyri...)
Affinity DataKi:  93.8nMAssay Description:Inhibition of human cloned full length carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326109(1,4-Dihydro-4-oxo-1-(3-sulfamoylpyrid-4-yl)-3-pyri...)
Affinity DataKi:  7.13E+3nMAssay Description:Inhibition of human cloned CA1 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326109(1,4-Dihydro-4-oxo-1-(3-sulfamoylpyrid-4-yl)-3-pyri...)
Affinity DataKi:  7.13E+3nMAssay Description:Inhibition of human cloned carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed