BDBM50326108 1,4-Dihydro-1-(2,4-dinitrophenyl)-4-oxo-3-pyridinesulfonamide::CHEMBL1242889

SMILES NS(=O)(=O)c1cn(ccc1=O)-c1ccc(cc1[N+]([O-])=O)[N+]([O-])=O

InChI Key InChIKey=GEDYQQXTTMSJSG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50326108   

TargetCarbonic anhydrase 9(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326108(1,4-Dihydro-1-(2,4-dinitrophenyl)-4-oxo-3-pyridine...)
Affinity DataKi:  5.80nMAssay Description:Inhibition of human cloned catalytic domain of CA9 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326108(1,4-Dihydro-1-(2,4-dinitrophenyl)-4-oxo-3-pyridine...)
Affinity DataKi:  34.6nMAssay Description:Inhibition of human cloned catalytic domain of CA12 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326108(1,4-Dihydro-1-(2,4-dinitrophenyl)-4-oxo-3-pyridine...)
Affinity DataKi:  97nMAssay Description:Inhibition of human cloned CA2 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50326108(1,4-Dihydro-1-(2,4-dinitrophenyl)-4-oxo-3-pyridine...)
Affinity DataKi:  6.10E+3nMAssay Description:Inhibition of human cloned CA1 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed