BDBM50326089 (E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitrophenyl)acryloyl)-N-(2-(4-methylpiperazin-1-yl)ethyl)benzamide::CHEMBL1242298

SMILES CN1CCN(CCNC(=O)c2ccc(cc2)C(=O)C(\SCc2ccc(Br)cc2)=C/c2ccc(F)c(c2)[N+]([O-])=O)CC1

InChI Key InChIKey=BIXQXDFSCQWEKU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326089   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Temple University

Curated by ChEMBL

LigandBDBM50326089((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitroph...)Copy SMILESCopy InChI

Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/11/2011
Entry Details Article
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