BDBM50326082 (E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-methoxyphenyl)acryloyl)benzoic acid::CHEMBL1241953

SMILES COc1cc(\C=C(\SCc2ccc(Br)cc2)C(=O)c2ccc(cc2)C(O)=O)ccc1F

InChI Key InChIKey=ZHTVLZPADKXPAJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326082   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Temple University

Curated by ChEMBL

LigandBDBM50326082((E)-4-(2-(4-Bromobenzylthio)-3-(4-fluoro-3-methoxy...)Copy SMILESCopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/11/2011
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