BDBM50326065 (E)-4-(2-(4-Fluorobenzylthio)-3-(4-chloro-3-nitrophenyl)acryloyl)benzoic acid::CHEMBL1242669

SMILES OC(=O)c1ccc(cc1)C(=O)C(\SCc1ccc(F)cc1)=C/c1ccc(Cl)c(c1)[N+]([O-])=O

InChI Key InChIKey=JOTZIFWMMIGBPN-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326065   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Temple University

Curated by ChEMBL

LigandBDBM50326065((E)-4-(2-(4-Fluorobenzylthio)-3-(4-chloro-3-nitrop...)Copy SMILESCopy InChI

Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/11/2011
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL