BDBM50326001 1-(2,4-difluorophenyl)-3-(4-(6,7-dimethoxyquinolin-4-yloxy)-2-methylphenyl)urea::CHEMBL1242557

SMILES COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccc(F)cc4F)c(C)c3)c2cc1OC

InChI Key InChIKey=REWMPRKUAPYNBX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326001   

TargetVascular endothelial growth factor receptor 2(Human)
Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50326001(1-(2,4-difluorophenyl)-3-(4-(6,7-dimethoxyquinolin...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of VEGFR-2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50326001(1-(2,4-difluorophenyl)-3-(4-(6,7-dimethoxyquinolin...)
Affinity DataIC50: 67nMAssay Description:Inhibition of PDGFRalpha kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMed