BDBM50325939 CHEMBL611368::Licocoumarone

SMILES [#6]-[#8]-c1c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])cc2oc(cc12)-c1ccc(-[#8])cc1-[#8]

InChI Key InChIKey=RRXURUBOEKHUOR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325939   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Toho University

Curated by ChEMBL
LigandPNGBDBM50325939(Licocoumarone | CHEMBL611368)
Affinity DataIC50: 7.12E+4nMAssay Description:Inhibition of human recombinant PTP1B assessed as p-nitorphenol production after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
LigandPNGBDBM50325939(Licocoumarone | CHEMBL611368)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of N-terminal 6His-tagged recombinant human DYRK1A (674 to 763 residues) expressed in Escherichia coli BL21(DE3) using RARPGTPALRE as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed