BDBM50325787 8-(3-(difluoromethoxy)phenyl)-6-((4-(methylsulfonyl)phenoxy)methyl)quinoline::CHEMBL1223686

SMILES CS(=O)(=O)c1ccc(OCc2cc(-c3cccc(OC(F)F)c3)c3ncccc3c2)cc1

InChI Key InChIKey=FMDFPSUREAEZOZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50325787   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325787(8-(3-(difluoromethoxy)phenyl)-6-((4-(methylsulfony...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325787(8-(3-(difluoromethoxy)phenyl)-6-((4-(methylsulfony...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325787(8-(3-(difluoromethoxy)phenyl)-6-((4-(methylsulfony...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325787(8-(3-(difluoromethoxy)phenyl)-6-((4-(methylsulfony...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed