BDBM50325786 4-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)methoxy)phenyl)-2-methylbutan-2-ol::CHEMBL1221434

SMILES CC(C)(O)CCc1ccc(OCc2cc(-c3cccc(OC(F)F)c3)c3ncccc3c2)cc1

InChI Key InChIKey=KDAUXYRYNLBXOV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50325786   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325786(4-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human PDE5AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325786(4-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325786(4-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 151nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325786(4-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325786(4-(4-((8-(3-(difluoromethoxy)phenyl)quinolin-6-yl)...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed