BDBM50325672 5,7,4'-Trihydroxy-3'-methoxyflavanone::CHEMBL490170::HOMOERIODICTYOL

SMILES COc1cc(ccc1O)[C@@H]1CC(=O)c2c(O)cc(O)cc2O1

InChI Key InChIKey=FTODBIPDTXRIGS-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50325672   

TargetCytochrome P450 1A1(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(CHEMBL490170 | 5,7,4'-Trihydroxy-3'-methoxyflavano...)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of human CYP1A1 by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(CHEMBL490170 | 5,7,4'-Trihydroxy-3'-methoxyflavano...)
Affinity DataIC50: 3.78E+4nMAssay Description:Inhibition of human CYP1A2 by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(CHEMBL490170 | 5,7,4'-Trihydroxy-3'-methoxyflavano...)
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of human CYP1B1 by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(CHEMBL490170 | 5,7,4'-Trihydroxy-3'-methoxyflavano...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(CHEMBL490170 | 5,7,4'-Trihydroxy-3'-methoxyflavano...)
Affinity DataIC50: 240nMAssay Description:Inhibition of CYP1B1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(CHEMBL490170 | 5,7,4'-Trihydroxy-3'-methoxyflavano...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(CHEMBL490170 | 5,7,4'-Trihydroxy-3'-methoxyflavano...)
Affinity DataIC50: 240nMAssay Description:Inhibition of CYP1B1 in human liver microsomes using ethoxyresorufin as substrate preincubated for 2 mins followed by NADPH addition measured after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(CHEMBL490170 | 5,7,4'-Trihydroxy-3'-methoxyflavano...)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of CYP1A1 in human liver microsomes using ethoxyresorufin as substrate preincubated for 2 mins followed by NADPH addition measured after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50325672(CHEMBL490170 | 5,7,4'-Trihydroxy-3'-methoxyflavano...)
Affinity DataIC50: 3.78E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using ethoxyresorufin as substrate preincubated for 2 mins followed by NADPH addition measured after 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed