BDBM50325318 1-allyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-(4-fluorophenyl)-4-hydroxypyrrolidin-3-yl)methyl)piperidin-4-yl)-3-(4-(trifluoromethyl)benzyl)urea::CHEMBL1222768

SMILES O[C@@]1(CN(C[C@@H]1CN1CCC(CC1)N(CC=C)C(=O)NCc1ccc(cc1)C(F)(F)F)C(=O)C1CCCC1)c1ccc(F)cc1

InChI Key InChIKey=HPFFSZAQYZXAAC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325318   

TargetC-C chemokine receptor type 5(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50325318(1-allyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-...)
Affinity DataIC50: 38.3nMAssay Description:Inhibition of human CCR5 expressed in CHO cells assessed as inhibition of RANTES-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed