BDBM50325187 4-Methyl-6-(((3S,4S)-4-((3'-(trifluoromethyl)biphenyl-4-yl)methoxy)pyrrolidin-3-yl)methyl)pyridin-2-amine::CHEMBL1222745

SMILES Cc1cc(N)nc(C[C@@H]2CNC[C@@H]2OCc2ccc(cc2)-c2cccc(c2)C(F)(F)F)c1

InChI Key InChIKey=TUMFAAOTAQZRGI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50325187   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325187(4-Methyl-6-(((3S,4S)-4-((3'-(trifluoromethyl)biphe...)
Affinity DataKi:  820nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325187(4-Methyl-6-(((3S,4S)-4-((3'-(trifluoromethyl)biphe...)
Affinity DataKi:  1.36E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325187(4-Methyl-6-(((3S,4S)-4-((3'-(trifluoromethyl)biphe...)
Affinity DataKi:  3.73E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed