BDBM50325185 6-(((3S,4S)-4-((3'-Chlorobiphenyl-4-yl)methoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine::CHEMBL1222677

SMILES Cc1cc(N)nc(C[C@@H]2CNC[C@@H]2OCc2ccc(cc2)-c2cccc(F)c2)c1

InChI Key InChIKey=YFLMTTKOWRHZTR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50325185   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325185(6-(((3S,4S)-4-((3'-Chlorobiphenyl-4-yl)methoxy)pyr...)
Affinity DataKi:  750nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325185(6-(((3S,4S)-4-((3'-Chlorobiphenyl-4-yl)methoxy)pyr...)
Affinity DataKi:  1.33E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325185(6-(((3S,4S)-4-((3'-Chlorobiphenyl-4-yl)methoxy)pyr...)
Affinity DataKi:  3.95E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed