BDBM50325183 6-(((3R,4R/3S,4S)-4-(3-(4-Chloro-3-fluorophenoxy)-phenoxy)pyrrolidin-3-yl)methyl)pyridin-2-amine::CHEMBL1222675

SMILES Nc1cccc(C[C@@H]2CNC[C@@H]2Oc2cccc(Oc3ccc(Cl)c(F)c3)c2)n1

InChI Key InChIKey=ZDKTXUSNJNOZIM-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50325183   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325183(6-(((3R,4R/3S,4S)-4-(3-(4-Chloro-3-fluorophenoxy)-...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325183(6-(((3R,4R/3S,4S)-4-(3-(4-Chloro-3-fluorophenoxy)-...)
Affinity DataKi:  8.30E+3nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325183(6-(((3R,4R/3S,4S)-4-(3-(4-Chloro-3-fluorophenoxy)-...)
Affinity DataKi:  8.18E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed