BDBM50325181 6-(((3R,4R/3S,4S)-4-(3-(4-Fluorophenoxy)phenoxy)-pyrrolidin-3-yl)methyl)pyridin-2-amine::CHEMBL1222609

SMILES Nc1cccc(C[C@@H]2CNC[C@@H]2Oc2cccc(Oc3ccc(F)cc3)c2)n1

InChI Key InChIKey=YWYRKJCEZJWFPJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50325181   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325181(6-(((3R,4R/3S,4S)-4-(3-(4-Fluorophenoxy)phenoxy)-p...)
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325181(6-(((3R,4R/3S,4S)-4-(3-(4-Fluorophenoxy)phenoxy)-p...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325181(6-(((3R,4R/3S,4S)-4-(3-(4-Fluorophenoxy)phenoxy)-p...)
Affinity DataKi:  2.21E+5nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed