BDBM50325179 6-(((3R,4R/3S,4S)-4-(Biphenyl-4-yloxy)pyrrolidin-3-yl)-methyl)pyridin-2-amine::CHEMBL1222607

SMILES Nc1cccc(C[C@@H]2CNC[C@@H]2Oc2ccc(cc2)-c2ccccc2)n1

InChI Key InChIKey=KNERKZOFGJZSHK-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50325179   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325179(6-(((3R,4R/3S,4S)-4-(Biphenyl-4-yloxy)pyrrolidin-3...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325179(6-(((3R,4R/3S,4S)-4-(Biphenyl-4-yloxy)pyrrolidin-3...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50325179(6-(((3R,4R/3S,4S)-4-(Biphenyl-4-yloxy)pyrrolidin-3...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed